| abstract |
A novel compound having antibacterial activity is provided. The present invention relates to novel semi-synthetic macrolides and ketolides having antibacterial activity having the formula II and pharmaceutically acceptable salts, esters or prodrugs thereof; pharmaceutical compositions comprising such compounds A method for treating bacterial infection by administration of such compounds; and a process for the preparation of these compounds. More particularly, the present invention relates to C12-modified erythromycin macrolides and ketolide derivatives, compositions containing these compounds, methods for making these compounds, and methods for treating bacterial infections. [Selection figure] None |