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filingDate 2007-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2009-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2009545634-A
titleOfInvention Methods for relieving dry keratoconjunctivitis
abstract An improved method of increasing tear production is by intranasally administering a therapeutically effective amount of a capsaicinoid compound to a patient who lacks tear production. Incorporation of topical corticosteroids or local anesthetic compounds into nasal formulations as needed is used to reduce transient nasal irritation and burning sensations that can sometimes be associated with intranasal administration of capsaicinoids . The present invention provides the use of an effective amount of a composition comprising a capsaicinoid compound suitable for intranasal administration to the nasal mucosa, for example for the treatment of dry keratoconjunctivitis.
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