http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2009543770-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-454 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-496 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-454 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-541 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-415 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-422 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4155 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4178 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-439 |
| filingDate | 2007-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2009-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2009543770-A |
| titleOfInvention | Combinations of pyrazole derivatives for the inhibition of CDK and GSK |
| abstract | (A) Formula (0): [Chemical 1] [Where: X is a group R 1 -A-NR 4 -or a 5- or 6-membered carbocyclic or heterocyclic ring; A is a bond, SO 2 , C═O, NR g (C═O) or O (C═O), where R g is hydrogen or optionally substituted with hydroxy or C 1-4 alkoxy. May be C 1-4 hydrocarbyl; Y is a bond or an alkylene chain of 1 to 3 carbon atoms; R 1 is hydrogen, a carbocyclic or heterocyclic group having 3 to 12 ring members, or an optionally substituted C 1-8 hydrocarbyl group, wherein 1 or 2 of the carbon atoms of the hydrocarbyl group Each may be optionally substituted with an atom or group selected from O, S, NH, SO, SO 2 ; R 2 is hydrogen, halogen, C 1-4 alkoxy, or a C 1-4 hydrocarbyl group optionally substituted with halogen, hydroxy or C 1-4 alkoxy; R 3 is selected from hydrogen and carbocyclic and heterocyclic groups of 3 to 12 ring members; and R 4 is hydrogen or C optionally substituted with halogen, hydroxy or C 1-4 alkoxy. 1-4 Hydrocarbyl group. ] Or a salt or tautomer or N-oxide or solvate thereof; and (b) formula (I ′ ″): [Chemical formula 2] [Where: R 1 is 2,6-dichlorophenyl; R 2a and R 2b are both hydrogen; and R 3 is a group of formula (A): [Chemical 3] [Wherein R 4 is C 1-4 alkyl. ] It is. ] Or a salt or tautomer or N-oxide or solvate thereof, A combination comprising |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2021191762-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-7241134-B2 |
| priorityDate | 2006-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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