| abstract |
The present invention includes a composition for drug delivery of indrone (eg, ropinirole), or a pharmaceutically acceptable salt thereof. This composition may be, for example, a gel suitable for transdermal application. The compositions of the present invention generally comprise a hydroalcoholic excipient, one or more antioxidants, and one or more buffers, and the pH of the gel is typically about pH 7 and about pH 9. Between. The composition can further comprise additional components, for example, hydroalcoholic excipients can further include additional solvents, antioxidants, co-solvents, penetration enhancers, buffers, and / or gels. An agent may be included. This composition can be used to treat various neurological diseases. |