| abstract |
The present invention relates to general formula (I) wherein R 1 represents halogen, CN or NO 2 , R 2 represents hydrogen or halogen, n represents 1 or 2, and R 3 represents one or more And phenyl, substituted by halogen or C 1 -C 6 alkyl; or cyclohexyl], and therapeutically acceptable salts or solvates thereof. These compounds are useful as protease activated receptor-1 (par-1) antagonists, particularly in the treatment of thrombosis. |