abstract |
The present invention relates to CGRP receptor antagonists, pharmaceutical compositions thereof, and methods thereby treating CGRP receptor mediated diseases and conditions. The present invention provides a compound of formula I or a pharmaceutically acceptable salt thereof. These compounds are useful as antagonists of CGRP receptors and therefore treat CGRP-mediated symptoms. The present invention also provides its pharmaceutical composition and use thereby. The present invention further relates to compounds useful as ligands for the CGRP receptor, in particular antagonists to the CGRP receptor, pharmaceutical compositions thereof, and their use. |