http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2009538298-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D497-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D497-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-444 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-438 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-55 |
| filingDate | 2006-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2009-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2009538298-A |
| titleOfInvention | Novel lapachone compounds and methods of use thereof |
| abstract | The present invention provides a novel tricyclic spiro-oxathiin naphthoquinone derivative, a synthetic method for producing the derivative, and a method for inducing cell death and / or inhibiting the growth of cancer or precancerous cells. Use of a derivative is provided. The naphthoquinone derivative of the present invention is an analog of a compound known as β-lapachone (3,4-dihydro-2,2-dimethyl-2H-naphtho (1,2-b) pyran-5,6-dione). . In one embodiment, the present invention provides a method of treating a cell proliferative disorder. This method involves the treatment of a therapeutically effective amount of a compound of formula I, or a pharmaceutically acceptable salt thereof, or a prodrug or metabolite thereof, in combination with a pharmaceutically acceptable carrier. Administration to a subject. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022010322-A1 |
| priorityDate | 2006-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 726.