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filingDate 2007-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2009-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2009538272-A
titleOfInvention Improved dosing and scheduling of oligomers
abstract The present invention relates to a human having a proliferative disease by administering an effective amount of pretreatment to a patient prior to administering an effective amount of a nucleotide-based composition that suppresses overexpression of a target gene that causes the proliferative disease. It relates to a method for treating a patient. The present invention includes pretreatment with one or more of radiotherapy such as X-rays, proton beams, electron beams, hyperthermia, ultrasound therapy, chemotherapy, and biological therapy. The invention also relates to an improved dosing and scheduling sequence for treating patients in need of treatment with a nucleotide-based inhibitor of the gene expression of interest.
priorityDate 2006-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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