http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2009538118-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-52 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-10 |
| filingDate | 2007-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2009-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2009538118-A |
| titleOfInvention | Enzymatic production of 2-hydroxy-2-methylcarboxylic acid |
| abstract | The present invention relates to an enzymatic process for producing 2-hydroxy-2-methylcarboxylic acid from 3-hydroxycarboxylic acid, wherein 3-hydroxycarboxylic acid is produced in an aqueous reaction solution and / or the reaction Add to aqueous solution and incubate. The aqueous reaction solution has 3-hydroxycarboxylic acid-CoA-mutase activity and has both 3-hydroxycarbonyl-CoA-ester forming activity and 3-hydroxycarbonyl-CoA-ester isomerization activity; Contains units for converting 3-hydroxycarboxylic acid to the corresponding 2-hydroxy-2-methylcarboxylic acid, wherein 2-hydroxy-2-methylcarboxylic acid is obtained as an acid or in the form of its salt . In an advantageous embodiment, the unit having 3-hydroxycarboxylic acid-CoA-mutase activity comprises a unit comprising an isolated cobalamin-dependent mutase, and optionally a 3-hydroxycarbonyl-CoA-ester producing enzyme or enzyme system, Or it is the microorganisms containing these. Advantageously, the present invention relates to a process for the biotechnological production of 2-hydroxy-2-methylcarboxylic acid, in which microorganisms having the desired activity are cultured using simple natural products in an aqueous system, The 3-hydroxycarbonyl-CoA-ester generated in the cell is converted into the corresponding 2-hydroxy-2-methylcarboxylic acid. The invention likewise includes the preparation of unsaturated 2-methylcarboxylic acids, in which case the obtained 2-hydroxy-2-methylcarboxylic acid is dehydrated to the corresponding unsaturated 2-methylcarboxylic acid (methacrylic acid and higher Homologue). |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10294500-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10851392-B2 |
| priorityDate | 2006-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 84.