| abstract |
Disclosed are compounds and related synthetic methods, and the use of compounds and combination therapies in the treatment of cancer and in the regulation of cellular apoptosis. In particular, phosphonic acid esters are disclosed. Compounds, methods of making compounds, pharmaceuticals and methods of manufacturing pharmaceuticals, and methods of treatment using application to cancer, including breast cancer, melanoma, colon cancer, leukemia and lymphoma, and other cancer cells are described. [Selection] Figure 3 |