| abstract |
The present invention relates to cholinergic ligands at nicotinic acetylcholine receptors and novel 1,4-diaza-bicyclo [3.2.2] nonane derivatives that have been found to be modulators of monoamine receptors and transporters About. Due to their pharmacological properties, the compounds of the present invention can be used in various diseases or disorders such as those related to the cholinergic system of the central nervous system (CNS), peripheral nervous system (PNS), diseases related to smooth muscle contraction or It may be useful in the treatment of disorders, endocrine diseases or disorders, diseases or disorders related to neurodegeneration, diseases or disorders related to inflammation, pain, and withdrawal symptoms caused by withdrawal of chemical abuse. |