| abstract |
The present invention includes pathological progression of angiogenesis, including ophthalmic diseases such as cancer or B-cell malignancies or diabetic retinopathy plus age-related macular degeneration (AMD), corneal neovascularization and retinopathy of prematurity It relates to derivatives of borrelidin that are useful in pharmaceuticals, such as in the treatment of other diseases that are responsible for the disease. The present invention relates to a process for the production of these compounds and their use in pharmaceuticals, in particular in the treatment and / or prevention of cancer or B-cell malignancies and other diseases in which angiogenesis is involved in the pathological progression process. Also provide. [Selection figure] None |