abstract |
Methods, compositions and kits are used to effectively treat and prevent cancer metastasis in vivo and to increase the survival rate of subjects bearing metastatic tumors, lysyl oxidase or its modulators, particularly human lysyl oxidase. Provide by targeting. Also, methods for identifying lysyl oxidase inhibitors (inhibitors), and the use of such inhibitors, alone and in combination with chemotherapeutic agents to prevent and treat tumors, particularly metastatic tumors Provide in. In addition, the use of lysyl oxidase levels to measure metastatic potential and viability is disclosed. |