abstract |
The present invention relates to a method for determining the presence of a particular HLA allele, such as HLA-B * 1502 or HLA-B * 5801, and a kit for carrying out the method. Based on the presence or absence of genetic markers (eg, HLA-B * 1502, HLA-B * 5801, or HLA-B * 4601), patients may experience drug side effects (eg, Steven-Johnson syndrome, toxic epidermolysis Also disclosed is a method of assessing whether there is a risk of causing hypersensitivity syndrome). |