abstract |
Compounds of formula I that are antagonists of CGPR receptors and are useful for the treatment or prevention of diseases involving CGRP, such as migraine: I (variables A 1 , A 2 , A 3 , A 4 , m, n, J, Q, R 4 , E a , E b , E c , R 6 , R 7 , R e , R f , R PG and Y are defined in the specification). The invention also relates to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved. [Chemical 1] |