http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2009535361-A
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-165 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-166 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-403 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-407 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0048 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K33-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K33-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-165 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-407 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P27-02 |
filingDate | 2007-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2009-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2009535361-A |
titleOfInvention | Formulations containing amide derivatives of carboxylic acid NSAIDs for topical administration to the eye |
abstract | Disclosed are topical compositions of amide derivatives of carboxylic acid non-steroidal anti-inflammatory agents. The compositions of the present invention are less likely to cause mitochondrial swelling when administered topically to the eye. The present invention also relates to a method of treating an ocular inflammatory disorder in a mammal in need of treating the ocular inflammatory disorder. In one embodiment of the present invention, an anti-inflammatory effective amount of an amide derivative of a carboxylic acid NSAID, an amount of sulfite effective to attenuate or prevent mitochondrial swelling and cytochrome c release, and an ocular acceptor A composition comprising a vehicle capable of being administered topically to a mammalian eye. |
priorityDate | 2006-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 85.