abstract |
Thienopyrimidines of formula (I) and their pharmaceutically acceptable salts are active as inhibitors of PI3K with selectivity for the P110 subtype and are diseases or disorders resulting from abnormal cell proliferation, function or behavior In particular, it can be used to treat diseases or disorders associated with PI3 kinase, such as cancer, immune diseases, cardiovascular diseases, viral infections, inflammation, metabolic / endocrine diseases and neurological diseases. A synthetic process for the above compounds is also described. |