abstract |
The present invention (A) Formula (I) (Wherein R 1 represents an optionally substituted monocyclic nitrogen-containing heterocyclic group having a hydrogen atom that can be deprotonated, R 2 represents an optionally esterified carboxyl group, and R 3 Represents lower alkyl which may be substituted) A nucleus containing a compound represented by the formula (1) or a salt thereof or a prodrug thereof and a low melting point oily substance; (B) a first layer containing a high molecular weight polymer and covering the nucleus; (C) Provided is a solid pharmaceutical composition comprising pioglitazone hydrochloride and a second layer covering the first layer. [Selection figure] None |