| abstract |
The present invention relates to conditions resulting from local estrogen deficiency, such as sexual pain, vulvar atrophy, vaginal atrophy, vaginal dryness, vulvar itching, vaginal itching, vulvar burning sensation, vaginal burning sensation, vulvar dystrophy, atrophy The present invention relates to a method for the prevention and treatment of vaginosis or menopausal dysfunction. In some embodiments, the methods of the invention include systemic administration of estrogen, such as conjugated estrogens, and progestagen, such as MPA, such as oral administration, and simultaneously topical administration of estrogens, such as conjugated estrogens. In some embodiments, the methods of the invention include oral administration of conjugated estrogens and MPA, and vulvar, vaginal or vulvar and vaginal administration of conjugated estrogens, for example in creams. |