| abstract |
Various pentosan polysulfate (PPS) formulations are provided that are useful for the treatment of osteoarthritis, interstitial cystitis, and other conditions in mammals. These formulations showed improved resistance to degradation and discoloration and improved stability at physiological pH even after sterilization. Capillary electrophoretic analysis of these formulations shows that the various formulations are stable under conditions that caused degradation of PPS in prior art PPS formulations. [Selection] FIG. |