| abstract |
Prostate cancer is the second most common cause of cancer death in men. The present invention relates to prostate cell surface antigen (PSCA), a protein that is overexpressed in various cancers, including these cancers, particularly for the diagnosis, prognosis provision, and cancer imaging of prostate cancer, bladder cancer, and pancreatic cancer. Novel humanized antibody fragments that specifically bind to are provided. Further, for using the compositions of the present invention for overexpressing cell surface PSCA, for cancer treatment, for cancer diagnosis, to provide a prognosis of cancer progression, and for cancer imaging Provide a method. |