http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2009530600-A
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-143333 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-54373 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-55 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-543 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-27 |
filingDate | 2007-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2009-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2009530600-A |
titleOfInvention | A method for measuring molecular interactions by measuring light reflected by a flat surface. |
abstract | A method for determining the binding constant of the interaction of a ligand with a receptor comprising: a flat surface of a transparent solid material comprising a hydrophobic amorphous polymer and having a refractive index of 1.32 to 1.35; Or contacting the solution containing the reagent; adding a series of known volumes of the aqueous ligand solution to the solution; and measuring the light intensity value reflected from the interface between the solid material and the aqueous solution for each additional time A method comprising: fitting the measured value as a function of ligand addition in a Fresnel equation to obtain attached mass and fitting in a Langmuir equation to obtain a ligand-receptor affinity constant at equilibrium. |
priorityDate | 2006-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 20.