| abstract |
An aspect of the present invention provides a medical device that can be implanted or inserted, the medical device comprising: (a) one or more depressions containing at least one therapeutic agent; and (b) a therapeutic agent containing depression. And a nanoporous coating disposed on the therapeutic agent containing depression that regulates species transport to and from the exterior of the device. The implantable or insertable medical device is configured to perform a role beyond simple drug delivery, for example, mechanical and / or electrical functions within the body, among other functions. An advantage of the present invention is that a medical device is provided that releases a large amount of therapeutic agent far exceeding the pore volume within the nanoporous coating, while at the same time providing functionality beyond drug delivery. Such release is closer to or achieves a zero order rate process drug release profile. [Selection] Figure 1 |