abstract |
The present invention relates to cinnoline compounds of formula (I) which are PDE1 inhibitors, pharmaceutical compositions containing such compounds and methods for preparing such compounds. The present invention also relates to methods for treating diseases that can be treated by inhibition of the PDE10 enzyme, such as obesity, non-insulin dependent diabetes, schizophrenia, bipolar disorder, obsessive compulsive disorder. [Chemical 1] [Selection figure] None |