abstract |
The present invention relates to a compound of formula (I) as a selective inhibitor of the enzyme 11-β-hydroxysteroid dehydrogenase type 1 (11β-HSD1). For the treatment and prevention of 2-adamantyl urea derivatives of and metabolic syndrome, diabetes, insulin resistance, obesity, lipid disorders, glaucoma, osteoporosis, cognitive disorders, anxiety, depression, immune disorders, hypertension and other diseases and conditions Of such compounds. |