| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-602
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-114 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L29-085
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L29-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-10 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-07
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-82
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61M25-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61M25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61M25-01 |
| filingDate |
2007-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2009-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2009523584-A |
| titleOfInvention |
Medical device with PH-dependent drug release |
| abstract |
The present invention provides an intravascular device coated with a first domain comprising an alkaline formulation of polyethyleneimine diazeniumdiolate. Alkali ensures the stabilization of the polyethyleneimine diazeniumdiolate during processing of the medical device while allowing for controlled release of nitric oxide in use. The present invention is also coated with a first domain of polyethylenimine diazeniumdiolate and an outer layer that prevents or inhibits release of polyethylenimine diazeniumdiolate, particularly from the alkaline first domain, for use in the body. Providing medical devices. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-7125526-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2021121619-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2016510036-A |
| priorityDate |
2006-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |