| abstract |
Heterocyclic substituted bicyclic or tricyclic compounds of formula (I) or pharmaceutically acceptable salts or solvates of said compounds, isomers or racemic mixtures wherein Represents any double bond, the dashed line is optionally bonded or unbonded, resulting in a double or single bond as enabled by valence requirements, and A n , M n , U n , G n , J n , K n , R 9 , R 10 , R 11 , R 32 , R 33 , B and Het are as defined in the present invention, and the remaining substituents are defined herein. And the pharmaceutical compositions containing them and administering the compounds to treat thrombosis, atherosclerosis, restenosis, hypertension, angina, arrhythmia, heart failure and cancer related diseases A method is disclosed. Combination therapy with other cardiovascular agents is also claimed. |