| abstract |
The present invention relates to general formula (I) {Where, [Where: X represents CH, CH 2 , CH═CH, CH 2 CH 2 , CH 2 CH═CH or CH 2 CH 2 CH 2 ; R 2 is aryl, heteroaryl (these groups are each unsubstituted or mono- or poly-substituted), an aryl group or heteroaryl bonded via a C 1 -C 3 -alkyl group (these Each group is unsubstituted or mono- or poly-substituted) R 2 is aryl or heteroaryl (these groups are each unsubstituted or mono- or poly-substituted), an aryl group bonded via a C 1 -C 3 -alkyl chain (this group is non-substituted) Substituted or mono- or poly-substituted) R 3 and R 4 independently of one another represent H; C 1 -C 6 -alkyl (saturated or unsaturated, respectively branched or unbranched), wherein R 3 and R 4 Does not represent H at the same time, Or, the groups R 3 and R 4 together represent CH 2 CH 2 OCH 2 CH 2 or (CH 2 ) 3-6 . } It is related with the substituted oxadiazole derivative represented by these. The compound has an affinity for the μ-opioid receptor. |