http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2009520483-A
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D333-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D333-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P41-002 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-365 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-465 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-04 |
filingDate | 2006-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2009-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2009520483-A |
titleOfInvention | Enzymatic reduction to produce optically active alcohols |
abstract | The present invention relates to an optically active alcohol of the formula (I) wherein n is an integer from 0 to 5 and Cyc is an optionally substituted mononuclear or polynuclear saturated or unsaturated carbocyclic ring or Is a heterocycle, R 1 is halogen, SH, OH, NO 2 , NR 2 R 3 , or NR 2 R 3 R 4+ X − , where R 2 , R 3 , and R 4 are each independently And hydrogen, a lower alkyl group, or a lower alkoxy group, and X − is a counter ion. According to this method, (i) the polypeptide sequence of SEQ ID NO: 1 or (ii) up to 25% of amino acid residues relative to SEQ ID NO: 1 has been modified by deletion, insertion, substitution or a combination thereof. An alkanone of the formula (II), wherein n, Cyc and R 1 are as defined above, and having a polypeptide sequence which retains at least 50% of the enzyme activity of SEQ ID NO: 1 Incubate in medium containing The compound of formula (II) is enzymatically reduced to produce the compound of formula (I), and the product thus obtained is isolated. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2016528894-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-6993063-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10563225-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11306328-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2020110152-A |
priorityDate | 2005-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 282.