| abstract |
The present invention relates to G protein-coupled receptor for screening one or more candidate compounds as a modulator of weight gain or adiposity or body fat percentage in a subject or as a medicament for obesity and related conditions. The invention relates to a method of using a body (GPCR). Inverse agents and antagonists of the present invention are obesity and related, including hypertension, insulin resistance, metabolic syndrome, type 2 diabetes, dyslipidemia, atherosclerosis, coronary heart disease, and stroke It is useful as a therapeutic agent for the prevention or treatment of conditions. The agonists and partial agonists of the present invention are useful as therapeutic agents for the prevention or treatment of disorders ameliorated by weight gain, including but not limited to cachexia. |