abstract |
The present invention relates to novel diazabicyclic aryl derivatives that have been found to be cholinergic ligands at the nicotinic acetylcholine receptor and modulators of monoamine receptors and transporters. The compounds of the present invention, due to their pharmacological properties, have diseases or disorders related to the central nervous system (CNS), peripheral nervous system (PNS) cholinergic system, diseases or disorders related to smooth muscle contraction, endocrine It may also be useful for the treatment of various diseases or disorders such as diseases or disorders, diseases or disorders associated with neurodegeneration, inflammation, pain, and withdrawal symptoms or disorders caused by chemical misuse. |