http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2009518347-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J41-0083 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P5-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P5-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J63-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P15-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P15-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-565 |
| filingDate | 2006-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2009-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2009518347-A |
| titleOfInvention | 11β-Benzaldoxime derivatives of D-homoestradi-4,9-dien-3-one |
| abstract | The present invention is a compound of the formula (I) [wherein R 1 is a hydrogen atom, or C 1 -C 6 -alkyl, C 1 -C 6 -acyl, C 1 -C 4 -alkoxycarbonyl, C 1 -C 4 -Alkylthiocarbonyl, C 1 -C 6 -alkylaminocarbonyl, or arylaminocarbonyl group; and R 2 is a hydrogen atom, or C 1 -C 6 -alkyl or C 1 -C 6 -acyl group] And 11β-benzaldoxime of D-homoestradi-4,9-dien-3-one represented by: The compounds of formula (I) bind more strongly to the glucocorticoid receptor than to the progesterone receptor and are effective anti-glucocorticoids. According to the invention, they are suitable for the treatment and / or prevention of pathologies and / or diseases that contribute to androgen deficiency induced by glucocorticoids, in particular cortisol. |
| priorityDate | 2005-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 139.