| abstract |
The present invention provides compounds of formula I Embedded image [Wherein A, B, R 1, R 1a, R 2, R 2a, R 3 and R 3a are as described in the specification] N-cyclic sulfonamide compounds are provided. The compounds of formula I are useful for the treatment or prevention of cognitive diseases such as Alzheimer's disease. The invention also encompasses pharmaceutical compositions comprising a compound of formula I, methods of making the compound of formula I, and methods of treating cognitive disorders such as Alzheimer's disease. |