abstract |
The present invention relates to a compound of formula (I) Or a pharmaceutically acceptable salt thereof. These compounds are inhibitors of the microsomal prostaglandin E synthase-1 (mPGES-1) enzyme and thus pain from various diseases or conditions such as osteoarthritis, rheumatoid arthritis and acute or chronic pain and Useful for treating inflammation. Also included are methods and pharmaceutical compositions for treating mPGES-1 enzyme mediated diseases or conditions. |