abstract |
The present invention provides novel sulfonylurea compounds of formula (I) and their pharmaceutically acceptable derivatives, polymorphic and amorphous forms. Various forms of these compounds are effective platelet ADP receptor inhibitors, can be used in various pharmaceutical compositions, and are particularly effective for the prevention and / or treatment of cardiovascular diseases, particularly those associated with thrombosis. Is. The present invention includes the steps of preparing such compounds and forms and administering a therapeutically effective amount of a compound of formula (I) or a pharmaceutically acceptable salt or form thereof, and thrombosis and thrombosis related in mammals Also provided are methods for preventing or treating a disease state. |