| abstract |
The present invention provides novel plants that are resistant not only to 2,4-D and other phenoxyauxin herbicides, but also to aryloxyphenoxypropionate herbicides. Heretofore, there has been no prediction or suggestion that plants having both of these advantageous properties can be produced by the introduction of a single gene. The present invention also provides for the use of one or more enzymes of the present invention alone to provide broader and more robust weed control, increased treatment flexibility, and improved herbicide resistance management options. Or plants that produce “overlapping” with another herbicide resistance gene, preferably with a glyphosate resistance gene. More specifically, preferred enzymes and genes for use according to the present invention are referred to herein as AAD (aryloxysianoate dioxygenase) genes and proteins. α-ketoglutarate-dependent dioxygenase enzymes have not previously been reported to have the ability to degrade herbicides of different chemical classes and modes of action. This very new discovery is based on the possibility of significant herbicide-tolerant crop traits as well as the development of selectable marker technology. The present invention also includes related methods of controlling weeds. The present invention allows novel combinations of herbicides to be used in novel ways. Furthermore, the present invention provides a novel method of preventing and controlling the formation of weeds that are resistant (or naturally more resistant) to one or more herbicides such as glyphosate To do. Preferred enzymes and genes for use in the present invention, referred to herein as AAD-12 (aryloxyalkanoate dioxygenase (A ryloxy A lkanoate D ioxygenase) ). This highly novel discovery is the basis for the potential for significant herbicide-tolerant crop traits and selectable markers. |