| abstract |
A compound of formula (I) wherein A and B together represent a fused aromatic ring which may be substituted; D is a compound of formula (i) wherein Y 1 is selected from CH and N Y 2 is selected from CH and N, Y 3 is selected from CH, CF and N) and formula (ii) (wherein Q is O or S), and R D is the formula (C), wherein R N1 is selected from H and optionally substituted C 1-10 alkyl, X is selected from a single bond, NR N2 , CR C3 R C4 and C = O, and R N2 is Selected from H and optionally substituted C 1-10 alkyl, R C3 and R C4 are independently selected from H, R, C (═O) OR, wherein R is optionally substituted C 1 -10 alkyl, optionally substituted C 5-20 aryl or optionally substituted C 3-20 heterocyclyl, Y is selected from NR N3 and CR C1 R C2 , R C1 and R C2 are independently H, R, C (= O) OR, wherein R is an optionally substituted C 1-10 Alkyl, optionally substituted C 5-20 aryl or optionally substituted C 3-20 heterocyclyl, wherein R C1 and R C2 are substituted together with the carbon atom to which they are attached. Spiro-fused C 5-7 may form a carbocyclic or heterocyclic ring, and when X is a single bond, R N1 and R C2 together with the nitrogen and carbon atoms to which they are attached An optionally substituted C 5-7 heterocycle, and when X is CR C3 R C4 , R C2 and R C4 are doubled between atoms substituted with R C1 and R C3 Together, they may form additional bonds so that bonds occur. |