| abstract |
The present invention relates to the treatment of inflammatory skin diseases, disorders or conditions by modulating proteins that are normally regulated by caspase-8 in the skin or by increasing caspase-8 activity or levels in the skin or Regarding prevention. Another aspect of the invention relates to a method for diagnosing inflammatory skin disease, disorder or condition, or predisposition to develop the disease, disorder or condition in an individual. Further aspects of the invention relate to methods for identifying target proteins involved in the course or pathology of inflammatory skin diseases, disorders or symptoms, and methods for screening candidate compounds for treating the diseases, disorders or conditions. More particularly, the present invention relates to inflammatory skin diseases such as atopic dermatitis and psoriasis. |