abstract |
The present invention relates to new AGC kinase inhibitors, in particular compounds of formula I, II or III, or stereoisomers, tautomers, racemates, metabolites, pro- or pre-drugs, salts of I, II, III , Hydrates or solvates, wherein X, R1, R2, R3, R31, n and m have the meaning defined in the claims. In particular, the present invention relates more particularly to ROCK inhibitors, compositions containing such inhibitors, in particular pharmaceuticals, and to the use of such inhibitors in the treatment and prevention of diseases. |