| abstract |
Treatment methods using pulsed cavitation ultrasound therapy can include the initial process of the tissue disruption process, the retention, treatment, and feedback sub-processes, where the tissue disruption process is a spatio-temporal bubble that is observed In order to optimize the process based on cloud dynamics, it includes the generation and retention of a set of microbubbles and the use of feedback. This method provides for tissue fragmentation or erosion, tissue liquefaction, and enhanced delivery of therapeutic agents. Various feedback mechanisms allow for changes in ultrasound parameters, provide control over the pulse cavitation process, and allow the process to be adjusted for some applications. Such applications can include specific tissue erosion, bulk tissue homogenization, and delivery of therapeutic agents across barriers. |