http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2009508600-A
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3852 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3612 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3817 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-28 |
filingDate | 2006-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2009-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2009508600-A |
titleOfInvention | Implant for repairing cartilage defect and method for manufacturing implant |
abstract | To repair cartilage defects in human patients or livestock, such as full thickness articular cartilage defects, an implant (1) having an implant body (2) is used, the implant body comprising a natural cartilage matrix and cartilage It is covered by cells that have the ability to produce, preferably autologous cells. The implant body preferably consists of autologous cartilage tissue with live chondrocytes integrated therein, which is produced by in vitro tissue culture. The cells for generating the cartilage tissue and the cells for covering the surface of the implant body are preferably the same. These cells are produced by in vitro cell growth derived from chondrocytes isolated from a cartilage biopsy. Chondrocytes dedifferentiated during cell growth are particularly suitable for redifferentiation during tissue culture to generate and maintain the cartilage matrix of the implant body. Also, the cells attached to the surface of the implant body are chondrocytes that have been dedifferentiated by cell proliferation and have not been redifferentiated, and are therefore particularly suitable for fusion of implants in the defect. With the cells attached to the surface of the implant body, the implant fuses well with the living tissue around the defect. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10130479-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10874763-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11406735-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11413373-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2014514021-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2015523153-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2015523154-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2015523155-A |
priorityDate | 2005-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 26.