abstract |
The present invention includes O-desmethylvenlafaxine (ODV), selective serotonin and norepinephrine reuptake inhibitors, or pharmaceutically acceptable salts thereof, specifically eliminating the deleterious side effects associated with oral administration of ODV. A transdermal drug delivery device (ie, patch) is provided that provides the benefit of reducing or reducing. Also provided are methods of preparing and using these transdermal delivery systems to treat depression, anxiety disorders, vasomotor symptoms, and pain. |