abstract |
The present invention, obesity, obsessive / compulsive disorder, such as depression and anxiety, for the treatment of disorders associated with 5-HT 2C, as selective 5-HT 2C receptor agonists of formula ( 6) -substituted 2,3,4,5-tetrahydro-1H-benzo [d] azepine represented by I) (I) [wherein R 6 is —C≡C—R 10 , —CH═CR 11 R 11 ′ or an alkyl moiety optionally substituted with 1 to 6 fluoro substituents — (C 0 —C 8 ) alkyl-Ar 2 , as well as other substituents defined in the specification]. |