| abstract |
The present invention relates to an anti-adhesive agent having a multilayer structure, and in particular, a nanofiber structure base layer formed by electrospinning a hydrophobic biodegradable and biocompatible polymer, and a hydrophilic surface on the surface of the base layer. The present invention relates to an anti-adhesive agent having a multilayer structure and a method for producing the same, characterized in that it comprises a polymer layer formed by coating a functional biopolymer. The anti-adhesion agent according to the present invention has adhesion, flexibility, physical strength, and ease of operation (folding ability) to tissues and organs, which have been problems with conventional anti-adhesion agents in gel, solution, sponge, film, and nonwoven fabric forms. Ease), deformation during operation, biocompatibility, etc., improve anti-adhesion performance and ensure user convenience, and at the same time have a nanofiber structure, blood and By blocking the penetration and movement of cells, adhesion prevention performance can be improved and wound healing can be promoted. In addition, it can be operated and moved with a small surgical instrument without breaking or breaking even if it is folded or rolled, and can be easily applied to various surgical operations, is convenient to operate and minimizes foreign body reaction Can do. |