| Predicate |
Object |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C237-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C235-78
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C233-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C229-12 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C235-78
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C235-74
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C235-76
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C237-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-165 |
| filingDate |
2006-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2009-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2009505990-A |
| titleOfInvention |
Systemic and intrathecal effects of a series of novel phospholipase A2 inhibitors on hyperalgesia and spinal cord PGE2 release |
| abstract |
Phospholipase A 2 (PLA 2 ) folin is expressed in the spinal cord whose inhibition induces potent antihyperalgesia. PLA 2 inhibitor compounds comprising a common motif consisting of a 2-oxoamide with a hydrocarbon tail and 4 carbon tethers are provided. These compounds block group IVA calcium-dependent PLA 2 (cPLA 2 ) and / or group VIA calcium-independent PLA 2 (iPLA 2 ) and / or group V secreted PLA 2 (sPLA 2 ). |
| priorityDate |
2005-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |