abstract |
Provided are peptides derived from antibodies reactive to GPI-linked epitopes and functionally equivalent ligands. These peptides can be used in the therapy and diagnosis of various diseases, all of which are believed to be caused by the inappropriate presence of autoantibodies in the body that are reactive with GPI-linked epitopes. The mechanism of action of these autoantibodies that endanger the organism and cause disease as well as methods of disease prevention and autoantibody detection are further described. |