| abstract |
Novel compounds that interact with the histamine H3 receptor are defined. These compounds are particularly useful for the treatment of various diseases or conditions where histamine H3 interaction is beneficial. Thus, the compounds may find use in the treatment of diseases of the central nervous system, peripheral nervous system, cardiovascular system, pulmonary system, gastrointestinal system and endocrine system, for example. The novel compound has a core consisting of a 6-membered aromatic ring containing at least one nitrogen atom and two carbon atoms in the ring, and a carbon or nitrogen atom in the remaining position of the ring. |