abstract |
The present invention provides a preparation of a novel controlled release pharmaceutical formulation for the controlled delivery of a specific drug and a method of using the formulation in the treatment or prevention of thrombosis. A compound of formula (I) as an active ingredient wherein R 1 represents C 1-2 alkyl substituted by one or more fluoro substituents; R 2 represents hydrogen, hydroxy, methoxy or Ethoxy; n represents 0, 1 or 2] or a pharmaceutically acceptable salt thereof; and a pharmaceutically acceptable diluent or carrier; provided that the compound of formula (I) is in the form of a salt Only in some cases the formulation may contain iota-carrageenan and a neutral gelling polymer; a controlled release pharmaceutical composition; such a formulation is useful for the treatment of cardiovascular disorders. [Selection figure] None |