http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2009298731-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_aac831a6be8de686431c615fcce2d8ae |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-555 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P39-06 |
| filingDate | 2008-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_331b4da45aef5dd510e1f32a68177815 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_11eb518cd5e7189668d57fd1911683f2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_81ce50205ef71141582bb3e2cce51a94 |
| publicationDate | 2009-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2009298731-A |
| titleOfInvention | Metalloporphyrin complex suppressing oxidative damage and pharmaceutical composition using the same |
| abstract | Provided is an antioxidant capable of targeting mitochondria more effectively than by using an antioxidant whose target is unclear by selectively delivering an antioxidant to mitochondria. SOLUTION: General formula (1) (In the formula, M represents a metal atom for forming a complex, and Ar 1 , Ar 2 , Ar 3 , and Ar 4 are each independently a carbocyclic or heterocyclic group that may have a substituent. Represents an aromatic group, and one or two of Ar 1 , Ar 2 , Ar 3 , and Ar 4 represent a cationic hydrophilic group composed of an N, N′-disubstituted imidazole group, and the rest Or an amphiphilic metalloporphyrin complex having a hydrophilic group and a lipophilic group represented by the following formula: 3 or 2 represents a lipophilic group comprising a phenyl group which may have a substituent; Specifically, an amphiphilic metalloporphyrin complex having a log Pow value of -2 or more, which is a parameter of a partition coefficient in an octanol-water system, and a pharmaceutical composition comprising the same. [Selection figure] None |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2013542936-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103102353-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2018145248-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114349961-A |
| priorityDate | 2008-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 208.