| abstract |
【Task】 A simple method for producing a glycoside from an unprotected sugar is provided. SOLUTION: Using a haloformamidinium derivative as a dehydrating condensing agent, a glycoside thereof is produced in a single step in an aqueous solution from a sugar having a free hemiacetal hydroxy group. This method can be applied to longer sugar chains, bioactive oligosaccharides, drug delivery system carriers, surfactants, sugar drugs, enzyme activity measuring reagents, whitening agents, enzyme-catalyzed sugar chain synthesis reagents, glycopeptides, It is useful for producing substances for various uses such as glycoproteins, sugar chain polymers, sugar chain chips, and improving the water solubility of fat-soluble molecules. [Selection] Figure 1 |